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Measuring the temperature of medicine cool bags 2-8°C and 16-25°C

There are a few elements to consider when testing bags: the ambient temperature, the type of medication, and the static temperature of the medication itself. What interests us is the temperature of the medication itself (not the air around it).


  1. Syringes, vials and pre-filled pens filled with water
  2. Temperature controllers (we use a MadgeTech Thermocouple Datalogger, with 8 different temperature probes)
  3. A temperature-controlled black box that keeps the tested bag at a constant temperature

When testing a medicine cooler bag, we try to reproduce normal conditions of use as closely as possible. We first fill syringes, pens and bottles with water and place them in a household refrigerator, so that they are between 2 and 8°C.

We then prepare the bag by placing the gel packs in a freezer at -18°C for at least 14 hours. -18°C is the temperature of a standard household freezer.

We place the MadgeTech temperature probes in the syringes, pens and bottles filled with water, so that they measure the temperature of the liquid. These probes are connected to the MadgeTech temperature controller, which in turn is connected to a computer that records the temperature every minute. The vials, syringes and pens are then placed in the drug cooler bag to be tested, together with the properly frozen gel packs in the correct position.

The entire test takes place in a controlled temperature environment (black box) that is maintained at a constant temperature of 24.2°C. The computer records the temperature every minute for 12, 24 or 36 hours, depending on the bag being tested.

Why 24.2°C?

24.2°C is internationally considered an average ambient temperature and is also the temperature maintained inside aircraft. Since most people use medicine cooler bags to travel on airplanes, this is the reference temperature used to test isothermal bags.

What if I use my medicine cooler bag at a higher temperature?

If you use a medication cooler bag that has been tested to keep your medication between 2 and 8°C for 24 hours, at an ambient temperature of 30°C, it will not last as long as 24 hours. It might only take 12 or 13 hours.

At MediCooler we do our utmost to create bags that perform perfectly, but the performance of the bag is determined by the intrinsic limitations of the environment in which they are used.

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